Reproduction Abstracts

Pigs provide outstanding models of human genetic diseases due to the striking similarities to human anatomy, physiology and genetics. Pig induced pluripotent stem cells (piPSCs) have been generated for several years but the cloning efficiency using unsynchronized piPSCs was extremely low. Here, we reported a method to produce diploid cloned embryos from piPSCs which were synchronized to metaphase. The piPSCs cell line was established using a drug-inducible system and exhibit s...